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DeCS
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Descriptor English:
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Antigens, CD59
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Descriptor Spanish:
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Antígenos CD59
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Descriptor Portuguese:
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Antígenos CD59
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Synonyms English:
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CD59 Antigen
Membrane Inhibitor of Reactive Lysis
CD59 Antigens
Homologous Restriction Factor 20
HRF20
Membrane Attack Complex Inhibition Factor
MACIF
Protectin
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Tree Number:
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D12.776.395.550.448.140
D12.776.543.484.500.140
D12.776.543.550.418.140
D23.050.301.264.035.159
D23.101.100.110.159
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Definition English:
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Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234) |
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Indexing Annotation English:
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note entry term PROTECTIN; do not confuse with protectins, which are n-3PUFA-derived anti-inflammatory mediators; the SCR term protectin D1 is also available
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Pharmacological Action:
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Complement Inactivating Agents
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History Note English:
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1996; use CD59 ANTIGEN (NM) 1989-1995, for PROTECTIN use CATIONIC PROTEIN, URATE-CALCIUM OXALATE STONE (NM) 1996-1999
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Allowable Qualifiers English:
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Record Number:
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32839
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Unique Identifier:
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D018957
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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